摘要
笔者介绍了DNA的半保留复制和半不连续复制提出与确立的过程:沃森和克里克提出DNA半保留复制的思路;Meselson和Stahl的实验验证;冈崎提出不连续复制的思路,并通过步步深入的实验证实。
The process of proposition and establishment of DNA semiconservative replication and semidiscontinuous replication is introduced. Watson and Crick proposed DNA semiconservative replication, and its exprimental evidence was given by Meselson and Stahl. Okzaki proposed the discontinuous replication and obtained the exprimental evidence of semidiscontinuous replication.
出处
《自然杂志》
北大核心
2010年第4期229-235,共7页
Chinese Journal of Nature
关键词
半保留复制
半不连续复制
密度梯度离心法
脉冲标记实验
冈崎片段
尿嘧啶片段
semiconservative replication, semidiscontinuous replication, density-gradient centrifugation, pulse-labeling experiment, Okazaki fragment, dUMP fragment