期刊文献+

DNA半保留复制和半不连续复制的提出与确立 被引量:2

Proposition and Establishment of DNA Semiconservative Replication and Semidiscontinuous Replication
下载PDF
导出
摘要 笔者介绍了DNA的半保留复制和半不连续复制提出与确立的过程:沃森和克里克提出DNA半保留复制的思路;Meselson和Stahl的实验验证;冈崎提出不连续复制的思路,并通过步步深入的实验证实。 The process of proposition and establishment of DNA semiconservative replication and semidiscontinuous replication is introduced. Watson and Crick proposed DNA semiconservative replication, and its exprimental evidence was given by Meselson and Stahl. Okzaki proposed the discontinuous replication and obtained the exprimental evidence of semidiscontinuous replication.
作者 向义和
机构地区 清华大学物理系
出处 《自然杂志》 北大核心 2010年第4期229-235,共7页 Chinese Journal of Nature
关键词 半保留复制 半不连续复制 密度梯度离心法 脉冲标记实验 冈崎片段 尿嘧啶片段 semiconservative replication, semidiscontinuous replication, density-gradient centrifugation, pulse-labeling experiment, Okazaki fragment, dUMP fragment
  • 相关文献

参考文献12

  • 1WATSON J D, CRICK F H C. Genetical implications of the structure of deoxyribonucleic acid[J]. Nature, 1953,171 : 964- 967.
  • 2郜金荣,叶林柏.分子生物学[M].武汉:武汉大学出版社,2007.
  • 3FRUTONJS.蛋白质,酶和基因-化学与生物学的交互作用[M].昌增益,译.北京:清华大学出版社,2005:438-439.
  • 4sMESELSON M,STAHL F W. The replication of DNA in escherichia coli[J]. Proc Natl Acad Sci USA, 1958,44(7) :671-682.
  • 5OKAZAKI R, OKAZAKI T, SAKABE K, et al. Cold spring harbor symposia on quantitative biology[J]. Proc Natl Acad Sci USA, 1968,33:129-143.
  • 6OKAZAKI R,OKAZAKI T,SAKABE K, et al. Mechanism of DNA chain growth, I . possible discontinuity and unusual secondary structure of newly synthesized chains[J]. Proc Natl Acad Sci USA, 1968,59 : 598-605.
  • 7郑用链.基础分子生物学[M].北京:高等教育出版社,2007:93-96.
  • 8SUGIMOTO K, OKAZAKI T, OKAZAKI R. Mechanism of DNA chain growth, II. accumulation of newly synthesized short chains in E. coli infected with ligase-defective T4 phages [J]. Proc Natl Acad Sci USA, 1968,60:1356-1362.
  • 9TYE B K, NYMAN P, LEHMAN I R, et al. Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA[J]. Proc Natl Acad Sci USA, 1977,74 (1),154-157.
  • 10FREIFELDER D M. Molecular biology-a comprehensive introduction to prokaryotes and eukaryotes[M]. Jones and Bartlett Publishers, 1983 : 277-283.

共引文献4

同被引文献2

引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部