SPA法和DXA法测量前臂骨密度的比较及终末期肾病患者骨密度变化特点

COMPARISON OF SPA WITH DXA IN MEASUREMENT OF BONE MINERAL DENSITY OF FOREARM AND ITS CHARACTERISTIC IN PATIENTS WITH END STAGE RENAL DISEASE

目的：比较单光子吸收法（ＳＰＡ）和双能Ｘ线吸收法（ＤＸＡ）测量前臂骨密度上的结果，探讨ＳＰＡ的应用价值；比较尿毒症患者不同部位骨密度的情况。方法：分别用ＳＰＡ和ＤＸＡ对８７例１５岁～５０岁（平均３３７２岁）人群进行前臂骨远端１／３段骨密度进行测量与比较，并对１７例行血液透析治疗的尿毒症患者进行股骨、腰椎、桡骨远端骨密度的测量。结果：ＳＰＡ和ＤＸＡ的测量结果显著正相关（ｒ＝０９０７，Ｐ＜００１），尿毒症患者桡骨远端１／３部位骨密度的丢失速度较腰椎、股骨颈、大转子更明显。其Ｔ评分是它们的１８４～４２４倍。结论：ＳＰＡ具有一定的应用价值。在测量骨密度时应依据具体的疾病，选择合理的部位进行骨密度测量，从而提高诊断水平。

Objective:To compare single photon absorptiometry(SPA) with dual energy X ray absorptiometry(DXA) in measurement of bone mineral density(BMD) of forearm and to study about the usefulness of forearm BMD in clinical practice.Methods:We measured BMD of 87 healthy individuals aged 15 50 years(33 7 years) in the distal 1/3 segment of radius by using SPA and DXA with comparison of their results.The BMD of proximal femur,vertebra and distal radius were measured in 17 patients with uremia who underwent hemodialysis.Results:The result of SPA is correlated significantly with the DXA results( r =0 907, P <0 01),the bone loss rate in the distal 1/3 segment of radius is quicker than that in other segments in uremia patients,with 1 84 4 24 folder increasement of the T score in the former.Conclusion:In order to improve the diagnostic level,it is important to select a correct segment based on different disease for measurement of BMD.