反复自发性流产患者ATAb检测的临床意义

STUDIES ON THE RELATION OF ATAB TORECURRET SPORNTANEOUS ABORTION

目的探讨ＡＴＡｂ与反复自发性流产之间的关系。方法应用ＥＬＩＳＡ方法检测了１８６例自发性流产患者血清中ＡＴＡｂ，并以５６例正常育龄妇女作为对照。结果反复自发性流产患者血清中的ＡＴＡｂ阳性率为１８８２％，而正常对照组的阳性率为１９７％（Ｐ＜００１）。ＡＴＡｂ阳性率随流产次数的增加而增加（Ｐ＜００５），但与流产时孕期之间无明显关系。结论弓形体感染与反复自发性流产密切相关，尤其多次流产的患者检测ＡＴＡｂ更为重要。

Objective To explore the relationship betweeh the ATAb and recurret sporntaneous abortion. Methods The ATAb was detected by ELISA in 186 recurrent spontaneous aborting women and 56normal fertile women. Results The positive of ATAb in recurrent spintaneous aborting women was 1882%, while 1.79% in normal fertile women ( P <001). The positive rate of ATAb was positixely correlated to the number of abortions. But ATAb was not associated with pregnant time. Conclusion The ATAb is closely related to recurrent spontaneou abortion.It may be an important cauee for recurrent spintaneous abortion.