129例心力衰竭患者炎症因子和高凝标志物与其预后的关系被引量：2

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摘要目的研究心力衰竭(简称心衰)患者炎症因子和高凝标志物与其心脏功能和预后的关系。方法对129例心衰患者和40名健康对照组取空腹静脉血,测定血清炎症因子白细胞介素-1β(IL-1β)和白细胞介素-6(IL-6),测定血浆高凝标志物凝血酶抗凝血酶复合物(TAT)、D-二聚体和P-选择素,分析这些指标与心脏功能、心衰病因及生存期的关系。结果心衰患者炎症因子和高凝标志物水平显著高于对照组(P<0.01)。炎症因子和高凝标志物水平与NYHA心脏功能分级和患者的生存期显著相关(均P<0.01),但并未发现与心衰病因有关。结论入院初期炎症因子和高凝标志物水平与心脏功能损伤和患者生存期有关。

作者朱心怡张金龙洪小苏

机构地区苏州大学附属第二医院心内科

出处《苏州大学学报（医学版）》 CAS 北大核心 2010年第3期590-592,共3页 Suzhou University Journal of Medical Science

关键词白细胞介素-1Β 白细胞介素-6 凝血酶抗凝血酶复合物 D-二聚体 P-选择素心力衰竭预后

分类号 R541.61 [医药卫生—心血管疾病]

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