摘要
星形胶质细胞是中枢神经系统分布最广、数量最多的细胞群体,有着复杂的信号转导系统,通过释放许多神经递质、神经营养因子和细胞因子参与疼痛信号的转导与调控。另外,星形胶质细胞还参与外周和中枢水平神经病理性疼痛的形成和发展。本文主要就星形胶质细胞起源、分类、功能、激活,参与疼痛调节机制,以及与神经病理性疼痛关系等进行文献综述。
Astrocyte is the most amount cell population of the central nervous system,which has complex signal transduction pathway. Astrocyte involves in many physiological actions and pathological processes. Further more,Astrocyte plays an important role in neuropathic pain generation and development at central nerve system level,or at peripheral level. This paper reviewed the evolution of astrocyte and neuropathic pain research in recent years.
出处
《中国康复理论与实践》
CSCD
2010年第8期704-706,共3页
Chinese Journal of Rehabilitation Theory and Practice
基金
宁波市自然科学基金项目(2008A610091)
