早期肠内营养支持对胃癌病人术后的作用

Effect of Early Postoperative Enteral Nutrition in Patients with Gastric Cancer

目的:探讨胃癌病人术后早期肠内营养支持的临床效果。方法:40例胃癌术后病人随机分为全肠外营养(TPN)组和早期肠内营养(EEN)组。术前1天、术后第2天和第8天各测定营养指标和急性炎性指标;观察术后并发症、住院时间。结果:研究期间病人无死亡,无严重并发症;研究结束时,EEN组血清前清蛋白、外周血淋巴细胞总数明显高于TPN组;而IL-6、住院时间明显少于TPN组。结论:胃癌病人术后早期用肠内营养支持,能改善病人的营养状况,减轻炎性反应,缩短住院时间。

Objective：To evaluate the effect of early postoperative enteral nutrition in patients with gastric cancer. Methods：On the second postoperative day,40 patients were randomly divided into two groups. One group was given total parenteral nutrition （TPN group） and the other group was fed with enteral nutrition （EEN group）.All variables were measured before operation and on postoperative day 2 and 8.Blood was drawn at different time points to assess albumin ,prealbumin, transferrin, C-reactive protein ,IL-6 and TNF-α.Morbidity, mortality and length of hospital stay were also evaluated. Results：Neither mortality nor morbidity occurred in all patients during the period of study. After the study,the levels of serum prealbumin,total lymphocytes in the EEN group were significantly higher than the levels in the TPN group. The length of hospital stay in the EEN group were significantly lower than in the TPN group. Conclusion：Early postoperative enteral nutrition in patients with gastric cancer is safe, and also has the benefit effects of enhancing the body status of nutrition, and reducing the inflammatory response and the length of hospital stay.