原发性肺癌血清骨钙素水平与骨转移的关系

The Study of Correlation Between Serum Osteocalcin and Bone Metastases in Patients with Lung Cancer

目的:观察血清骨钙素水平与肺癌骨转移的关系。方法:应用Pharmacia CAP系统检测86例原发性肺癌和36例正常人血清骨钙素水平。结果:肺癌及其不同细胞类型病人之间以及与正常人比较,无骨转移者血清骨钙素水平无明显差异,伴有骨转移者血清骨钙素水平(6.26±1.68)明显高于无骨转移者(4.53±1.50)和正常人(4.56±1.53)(P<0.05)。结论:血清骨钙素检测对预示肺癌发生骨转移有参考价值。

Objective： To observe the correlation between serum level of osteocalcin and osseous metastasis caused by lung cancer.Method：The Pharmacia CAP system was employed to test the serum osteocalcin in 86 lung cancer patients and 36 healthy controls.Result：The difference of serum osteocalcin between healthy controls and patients without bone metastasis was not obviousp0.05.But the serum osteocalcin in patients with bone metastasis（6.26±1.68） were higher than those without bone metastasis（4.53±1.50） and（4.56±1.53）（P0.05）.Conclusion：The serum osteocalcin could be a good indication to diagnose osseous metastasis caused by lung cancer.