围绝经期综合征的植物疗法:兼论黑升麻的研究

Botanical Therapy for Relieving Menopausal Symptoms with Particular Reference to Cimicifuga Racemosa

妇女健康倡议(WHI)临床试验的结果提示,应着重关注传统的激素治疗围绝经期综合征的安全性。在围绝经期综合征治疗中,替代药物的地位可能会逐渐提升;大量设计良好的临床试验为其可信度提供支持性科学证据。传统医学史上长期应用的、具有药物特性的植物是治疗各种疾病的重要手段。以植物药为主的自然疗法也备受关注。如今,植物药应用于缓解围绝经期综合征已很普及,尤其是黑升麻已得到众多研究的认可。对缓解围绝经期综合征的植物药(主要是黑升麻)的安全性及有效性做文献综述。

Results from the Women＇s Health Initiative clinical trial have raised serious safety concerns for conventional hormone therapy in menopause symptoms management. For this reason alternative drugs may be more appropriate and the level of credibility in these alternatives is increasing since nowadays they are more frequently supported by evidence or scientific-based evaluations due to the growing number of well-designed clinical trials. Natural treatment of herbal origin are gradually gaining in importance and the development of phyto-pharmaceuticals recognizes the long-term use of botanicals in traditional medicine as therapeutic agents due to their medical properties. Nowadays ,the use of botanicals as a medical treatment approach for menopause symptoms relief is very popular and particularly black cohosh is one of the most widely used and studied herb in this indication. The aim of this paper is an review of the scientific literatures of botanicals which are commonly used for treatment of menopause symptoms and with main emphasis to efficacy and safety profile of black cohosb.