妊娠合并卵巢恶性肿瘤的诊断与治疗

Treatment and Diagnosis of Pregnancy Combined with Malignant Ovarian Tumor

妊娠合并卵巢恶性肿瘤极其少见,依靠影像学检查及血清标志物检查诊断多无困难。对于希望继续妊娠的卵巢恶性肿瘤患者的治疗,在妊娠早期主要是严密随访,包括影像学检查和血清标志物检查;妊娠中期可以进行简单的分期手术及活检,术后可进行辅助化疗;妊娠晚期剖宫产同时行卵巢恶性肿瘤全面分期手术,术后辅以足疗程化疗。妊娠能够促使肿瘤生长和转移,肿瘤生长及对其治疗可造成胎儿流产、早产、胎儿窘迫和胎儿生长受限等并发症。

Pregnancy combined with malignant ovarian tumor is extremely rare. It＇s easy to diagnosis by imaging examinations and serum markers. The treatment of the patients with malignant ovarian tumor who want to keep on gestation needs follow-up strictly in the first trimester, included imaging examinations and serum markers. Biopsy, a simple staging surgery, chemotherapy is managed in the second trimester. Cesarean section and comprehensive staging surgery are operated in third trimester, and postoperative chemotherapy needs be given completely. Pregnancy promotes growth and metastasis of tumor. Therapy and growth of tumor cause miscarriage, premature delivery ,fetal distress, fetal growth retardation and so on.