二乙烯基苯泡沫空心球微流体成型技术

Fabrication of divinylbenzene foam shells by microliquid technique

基于微流体成型技术,设计开发了一套用于微胶囊制备的T型微通道乳粒发生器,并利用该装置实现了二乙烯基苯空心泡沫微球的连续制备。以二乙烯基苯的邻苯二甲酸二丁酯溶液为油相,以聚乙烯醇的水溶液为外水相,去离子水为内水相,成功制备出二乙烯基苯双重微乳液,并采用水平旋转加热装置使其凝胶固化,再经过溶剂交换、CO2超临界干燥等过程,制备出直径700～1200μm、壁厚60～100μm、密度90～120mg.cm-3的二乙烯基苯空心泡沫微球。利用光学显微镜、扫描电镜和X-透射显微镜表征,结果显示:微胶囊球形度、同心度和壁厚均匀性较好,成活率较高,直径单分散性较好,外表面较粗糙。

Based on the microliquid technique,a T-microchannel droplet generator was designed and developed for the continuous fabrication of hollow foam micro-shells of controlled size. Solutions of an internal water phase,an oil phase （divinylbenzene（DVB） monomer,dibutylphthalate solvent,and azodiisobutyronitrile initiator）,and an external water phase were used in the fabrication of micro-shells. DVB hollow foam micro-shells of 700 to 1 200 μm in diameter and 60 to 100 μm in thickness were finally prepared in the density of 90 to 120 mg·cm-3 by level-rotation-heating,solvent exchanging and supercritical drying. Their morphology and diameter dispersivity were characterized by optical microscope,X-ray diffraction microscope and scanning electron microscope,etc. The results show that,the microcapsules has good sphericity,concentricity and thickness uniformity,as well as a high survival rate. The diameter monodispersity of the microcapsules is good,however,the surface is rough.