经尿道同期处理非肌层浸润性膀胱癌合并良性前列腺增生

Homochronous Transurethral Disposal of Non-muscle Invasive Bladder Cancer and Benign Prostatic Hyperplasia

目的探讨行经尿道膀胱肿瘤电汽化术和同期行经尿道前列腺电汽化术治疗非肌层浸润性膀胱癌合并良性前列腺增生的临床疗效。方法将42例非肌层浸润性膀胱癌合并良性前列腺增生患者按随机数字表法分为2组:治疗组和对照组,每组21例。治疗组患者行经尿道膀胱肿瘤电汽化术和同期行前列腺电汽化术,对照组患者行经尿道膀胱肿瘤电汽化术。观察2组患者术后非肌层浸润性膀胱癌的复发及有无前列腺部尿道肿瘤的种植等情况。结果 2组患者均随访2年。治疗组、对照组术后复发率分别为33.3%、38.1%,2组比较差异无统计学意义(P>0.05)。2组患者均无前列腺部尿道肿瘤的种植。结论非肌层浸润性膀胱癌合并良性前列腺增生行经尿道膀胱肿瘤电汽化术和同期行经尿道前列腺电汽化术治疗,不增加前列腺尿道肿瘤的种植风险,对非肌层浸润性膀胱癌术后复发无影响,是一种有效的治疗方法。

Objective To explore the clinical curative effect of homochronous transurethral disposal of the transurethral vaporization of bladder tumor（TVBT） and transurethral vaporization of prostatic（TVP） treatment in patients with non-muscle invasive bladder cancer together with benign prostatic hyperplasia（BPH）.Methods Forty-two patients with non-muscle invasive bladder cancer complicated with BPH were assigned into 2 groups according to the random number table.21 patients（treatment group） underwent both TVP and TVBT simultaneously.While the other 21 patients（control group） underwent TVBT alone.The non-muscle invasive bladder cancer in postoperative recurrence and the implanting of cancer in prostatic urethra were observed and compared between the two groups.Results All the patients were followed up for 2 years.The recurrence rates in postoperative of the treatment group and the control group were 33.3% and 38.1%,respectively.No statistically significant differences were found between these 2 groups（P〉0.05）.No cancer planting in prostatic urethra were observed in 2 groups.Conclusion Homochronous TVP and TVBT treatment in patients with non-muscle invasive bladder cancer complicated with BPH,increasing the risk of urethral tumor planting in prostatic urethra and the non-muscle invasive bladder cancer had no effect on recurrence,is an effective treatment.