哺乳动物雷帕霉素靶蛋白的研究进展

Update on the research of the mammalian target of rapamycin gene

哺乳动物雷帕霉素靶蛋白(mammalian target of rapamycin,mTOR)是细胞生长和增殖的重要调节因子。大量研究显示mTOR信号途径调控异常与细胞增殖密切相关。文中就mTOR基因及其靶基因,以及涉及的相关信号途径等方面进行综述。

Mammalian target of rapamycin（mTOR） is a significant regulator for cell growth and proliferation.Previous research has shown that the abnormity of mTOR signaling pathway is relational for cell proliferation.The signaling pathways of mTOR were recapitulated in this article.