高压氧对冠心病患者静息心率脉压和血脂的影响

Influences of Hyperbaric Oxygen on the Heart Rate,Pulse Pressure and Blood Lipids in Patients with Coronary Heart Disease

目的:了解高压氧(HBO)对冠心病患者静息心率、脉压和血脂的影响。方法:46例确诊为冠心病的患者列为冠心病组,另选择非冠心病的患者42例为对照组,均配合给予HBO治疗。治疗前后观察静息心率(RHR)、脉压(PP)和血脂的变化。结果:治疗前冠心病组RHR、PP及血脂TC、LDL-c、APOA1均明显高于对照组(P<0.05);治疗12～26d,平均(24±0.4)d后,与治疗前比较,RHR、PP、TC、TG、LDL-c均明显下降,HDL-c升高(P<0.05);与对照组比较,TC,LDL-c,ApoA1和Lp(a)仍较高,差异有显著性意义。对照组治疗后与治疗前比较,TC、TG及LDL-c均明显下降(P<0.05)。结论:HBO辅助治疗可降低冠心病患者RHR、PP及血脂,有助于冠心病的治疗。

Objective：To study the effect of hyperbaric oxygen （HBO） on resting heart rate （RHR）,pulse pressure （PP） and lipids of patients with coronary heart disease （CHD）. Methods：Forty-six cases of CHD served as CHD group,and 42 cases of non-CHD as control group. RHR,PP and lipids were checked before and after HBO treatment. Results：（1） RHR and PP were lower after HBO treatment than those befofe HBOT in CHD group （P0.05）. （2）TG,TC and LDL were reduced,and HDL was increased after HBOT in both two groups （P0.05）. （3） RHR and PP were significantly higher in CHD group than in contrlo group before treatment. TG,TC and LDL were also higher,and HDL was lower. Conclusion：HBO treatment can lower RHR,PP,TG,TC and LDL,and HDL is increased after HBO.