米氏酸在杂环化合物合成中的应用研究进展

Progress in Application of Meldrum’s Acid to Synthesis of Heterocyclic Compounds

综述了近年来米氏酸在杂环化合物合成中的应用,涉及到吡喃环、吡啶环、呋喃环、吡咯环、噁唑环和异噁唑环重要杂环的形成.大多具有反应条件温和、便利、产率较高等优点.

The applications of Meldrum’s acid to synthesis of heterocyclic compounds in recent years are reviewed. All the heterocyclic compounds are related to pyranoid, pyridine, furan, pyrrole, oxazole and isoxazole rings. Most mentioned synthetic methods have the advantages of mild reaction conditions, easy operation and high yields.