咪唑安定治疗小儿惊厥的疗效评价

Observation on effect of midazolam in the treatment of convulsive in children

目的研究咪唑安定持续静滴对小儿惊厥的疗效。方法选择71例SE患儿随机分为2组,其中咪唑安定组38例,持续静滴;对照组33例,应用咪唑安定肌内注射。结果治疗组疗效明显高于对照组(P<0.05)。结论持续静滴咪唑安定是治疗小儿惊厥安全有效的方法。

Objective To research the effect of continuous intravenous infusion midazolam in the treatment of convul- sive. Methods Seventy-one cases of children with SE were randomly divided into two groups：Treatment group of 38 cases were treated by midazolam continuous intravenous infusion; Control group of 33 cases were treated by valiumint ravenous which was the first line anti-epileptic agent. Results There was no significant different on the onset time between the two groups, the effect of treatment group was better than the controls （P〈0. 05）. Conclusion It is a safe and effective way to treat convulsive with continuous intravenous infusion midazolam.