病毒性肝炎患者多项血清检验指标与其预后的相关性研究及其护理

Correlation Study of the serum Test Index and the Prognosis in Viral Hepatitis and the Nursing

目的探讨重型病毒性肝炎患者多项血清检验指标与其预后的相关性及护理方法。方法选取2008年1月～2009年5月于我院进行治疗的60例重型病毒性肝炎患者为研究对象,将其设为观察组,同时选取60名健康人为对照组,对其采用相应的护理及治疗,后将两组人员的血清胆碱酯酶(CHE)、凝血酶原活动度(PTA)、血清胆固醇(Chol)、甲胎蛋白(AFP)、CRP及补体C3水平进行检测及比较。结果经研究比较发现,观察组的CHE、PTA、Chol及补体C3水平均显著低于对照组,P均<0.01,有非常显著性差异,而CRP及AFP水平则显著高于对照组,P<0.01。且最终死亡患者的差异更大。结论病毒性肝炎患者CHE、PTA、Chol、AFP、CRP及补体C3水平与其预后的相关性较大,值得临床进一步研究。

Objective To study the correlation of the serum test index and the progonosis in severe viral hepatitis and the nursing methods. Methods 60 eases with severe viral hepatitis hospitalized in the period from Jan. , 2008 to May, 2009 were selected to form the observation group and 60 normal the control group; related treatment and nursing were performed, and then the levels of CHE, PTA, Chol, AFP, CRP and complement C3 of the eases in both groups were deteeted and the results were analyzed. Results The levels of CHE, PTA, Chol and complement C3 of the eases in observation group were much lower than those in control group and the difference was of significance （ P 〈 0. 01 ） ; the levels of CRP and AFP of the patients in observation group were higher than those in control group （ P 〈 0. 01 ） ; a bigger differ- enee of the levels existed between the cases who died at last and the survivals. Conclusions The levels of CHE, PTA, Chol, AFP, CRP and complement C3 of the patients with severe viral hepatitis are greatly correlated to the prognosis.