中分子羟乙基淀粉注射液治疗急性脑分水岭梗死的疗效观察

Effect of medium-molecular-weight hydroxyethyl starch in the patients with acute cerebral watershed infarction

目的观察中分子羟乙基淀粉注射液治疗急性脑分水岭梗死的疗效。方法利用日常生活活动能力量表(Barthel index,BI)和治疗后90d改良Rankin量表评价中分子羟乙基淀粉注射液治疗患者(治疗组)和常规治疗患者(对照组)的临床疗效。结果治疗后7、14d,治疗组BI上升,日常生活能力明显高于对照组。治疗后90d,治疗组的致残程度明显轻于对照组。结论中分子羟乙基淀粉注射液治疗急性脑分水岭梗死,可以改善患者日常生活能力、90d的残疾程度。

Objective To observe the efficacy and safety of medium molecular weight hydroxyethyl starch in the treatment of patients with acute cerebral watershed infarction. Methods Clinical curative effects of medium molecular weight hydroxyethyl starch treatment patients （treatment group patients） and conventional therapy patients （control group） were evaluated by Barthel index （BI） scale and the modified Rankin scale（mRS） after treatment of 90 days. Results Seven and fourteen days after treatment, Barthel index in the treatment group rised and activities of daily living were significantly higher. Ninety days after treatment, disability in the treatment group was lighter than that in control group. Conclusion Daily living skills of the patients with acute cerebral watershed infarction were improved by medium molecular weight hydroxyethyl starch treatment; the degree of disability of 90 days after treatment was reduced.