达菲及中药治疗甲型H1N1流感的疗效观察

Curative effect observation of Tamiflu and traditional Chinese medicine on type A H1N1 influenza

目的探讨奥司他韦(达菲)及中药对甲型H1N1流感的临床疗效。方法将2009年5—10月本院收治的187例甲型H1N1流感患者随机分为达菲组、中药组及对照组3组,观察3组在热程、症状持续时间、核酸转阴时间、是否出现肺炎等方面的区别。结果达菲组及中药组的发热时间及症状持续时间均短于对照组(P均<0.05);核酸转阴时间及是否出现肺炎方面,3组间比较均无显著性差异(P均>0.05)。结论达菲及中药均可有效缩短发热时间及改善临床症状,超过36 h服用达菲对缩短发热时间及改善临床症状仍有效,但抗病毒效果有限。

Objective It is to approach the clinical curative effect of oseltamivir（Tamiflu） and traditional Chinese medicine（TCM） on type A H1N1 influenza.Methods 187 patients with type A H1N1 influenza in our hospital from May 2009 to October 2009 were randomly divided into Tamiflu group,TCM group and control group.The differences of fever time,duration of symptoms,nucleic acid turning negative time and whether there is pneumonia or not among the three groups were observed.Results The fever time and duration of symptoms in Tamiflu group and TCM group were all shorter than that in control group（all P〈0.05）.There were no significant differences on nucleic acid turning negative time and whether there is pneumonia or not among the three groups（all P〉0.05）.Conclusion Tamiflu and TCM can both effectively shorten fever time and improve clinical symptom.Tamiflu taken after more than 36 h also can effectively shorten fever time and improve clinical symptom,but has limited effect of anti-virus.