孟鲁司特联合氟替卡松预防婴幼儿哮喘急性发作

Combined administration of montelukast and inhaled fluticasone in prevention of infant asthma

目的观察孟鲁司特联合氟替卡松防治婴幼儿哮喘的临床疗效。方法采用随机分组的方法 ,将72例婴幼儿哮喘分为2组:治疗组36例给予氟替卡松吸入,同时口服孟鲁司特;对照组36例仅吸入氟替卡松,连用6个月。结果治疗组的临床疗效明显优于对照组,差异有统计学意义(P<0.01)。结论孟鲁司特联合吸入氟替卡松较单一吸入氟替卡松疗效好,可降低复发率。

Objective To investigate the therapeutic effect of the combined administration of montelukast and inhaled fluticasone on asthmatic infant. Methods 72 cases were randomly divided into two groups. The control group of 36 cases were treated with inhaled flnticasone and the therapy group of 36 cases with the combination of montelukast and inhaled fluticasone. The duration of treatment was 6 months. Results The therapy group was better than the control group （ P 〈 0.01 ）. Conclusion The combination of montelukast and inhaled fluticasone is more effective than mere inhaled fluticasone, and it can reduce the rate of recurrence as well.