^(13)C-UBT对消化科住院病人幽门螺杆菌感染的诊断价值

目的评价13C-尿素呼气试验(13C-UBT)诊断消化科住院病人幽门螺杆菌感染的临床价值。方法选择81例本院内科因消化道症状就诊的住院患者行胃镜检查时同时取标本进行快速尿素酶试验(RUT)及病理组织学检测,胃镜检查结束后立即做13C-UBT检测。以内镜检查结果作为诊断HP感染的金标准,计算13C-尿素呼气试验诊断幽门螺杆菌感染的准确率、敏感性、特异性、阳性预测值和阴性预测值。结果 13C-尿素呼气试验的诊断准确率为93.8%,敏感性91.9%,特异性95.5%,阳性预测值94.4%,阴性预测值93.3%。结论 13C-UBT诊断消化科住院病人HP感染有较高的敏感性和特异性,是测定消化科住院病人Hp感染的一种可靠诊断方法。

Objective To investigate the diagnostic value of 13C-Urea Breath Test for Helicobacter pylori infection in inpatients of gastroenternology.Methods Two mucosal biopsy specimens were obtained during endoscopy of 81 inpatients of gastroenterology for rapid urea test and histology.And each patient received C-Urea Breath Test（UBT） after endoscopy.The results of rapid urea test and histology were set as the gold standard,and the 13C-Urea Breath Test compared against them to calculate the accuracy,sensitivity,specificity,positive predictive value and negative predictive value.Results The accuracy,sensitivity,specificity,positive predictive value and negative predictive value of UBT were 93.8%,91.9%,95.5%,94.4% and 93.3% respectively.Conclusion 13C-Urea Breath Test has a high sensitivity and specificity for the diagnosis of Helicobacter pylori infection,and can be recommended as a reliable diagnostic test for H.pylori infection.