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甲状腺功能异常与脑梗死的关系 被引量:2

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摘要 目的了解甲状腺功能(简称甲功)异常与脑梗死之间的关系。方法甲功异常合并脑梗死住院患者133例,按甲功情况分为甲状腺功能亢进症组(简称甲亢组,83例),甲状腺功能减退组(简称甲减组,50例),并以30例健康体检者作为对照组。三组均于清晨(甲亢、甲减组患者为入院次日,对照组体检者为体检当日)行甲功、血脂、血糖和胰岛素、血同型半胱氨酸、心电图等检测。结果甲亢组空腹血糖和胰岛素均明显高于甲低组及对照组(P<0.01)。总胆固醇及高密度脂蛋白显著低于甲低组与对照组(P<0.01)。而甲减组胆固醇及血同型半胱氨酸明显高于甲亢组和对照组(P<0.01)。心电图示70%以上脑梗死患者并有心律失常,甲亢组以窦性心动过速及心房纤颤多见;甲减组以窦性动过缓及心力衰竭为主。结论甲功异常特别是甲亢患者空腹血糖增高、血脂代谢异常;而甲减者同型半胱氨酸增高,导致的心律失常进一步加重血液动力学的改变,加速脑梗死的发生。甲功异常可能是脑梗死的重要危险因素。
出处 《广东医学院学报》 2010年第3期278-279,共2页 Journal of Guangdong Medical College
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