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一种糖尿病动物模型基因芯片的聚类分析

Cluster Analysis on Gene Chips of a Diabetic Animal Model
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摘要 建立一种基因表达谱的聚类分析模型,通过信噪比处理、聚类结果的分析比较、相应标记的寻找,为芯片数据的后续分析以及寻找差异基因提供一种有效的方法.对一种糖尿病动物模型的小鼠基因表达谱进行实际分析,获取了有意义的结果,从而为糖尿病的快速和早期临床医学诊断提供有效的技术支撑. This paper introduces a model of cluster analysis on the gene expression data. By processing signal-to-noise ratio, comparing the cluster analysis results and searching the corresponding markers, it offers an efficient method to post-analyze the gene expression data and discover different genes. Gene expression data of a diabetic mouse are analyzed, and significance of this analysis obtained, which facilitates technical support to rapid and early clinical diagnosis of diabetes.
机构地区 上海大学理学院
出处 《上海大学学报(自然科学版)》 CAS CSCD 北大核心 2010年第4期409-414,共6页 Journal of Shanghai University:Natural Science Edition
基金 国家自然科学基金资助项目(30871341) 上海市重点学科建设资助项目(S30104) 上海市教委重点学科建设资助项目(J50101)
关键词 基因表达谱 过程模型 聚类分析 差异基因 gene expression profiles process model cluster analysis different gene
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参考文献11

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