摘要
目的:观察复方胆通片治疗对肝硬化患者血清球蛋白等的影响。方法:60例乙肝肝硬化患者随机均分为空白组、对照组与实验组,患者均接受抗病毒等常规治疗,对照组加用熊去氧胆酸胶囊,实验组加用复方胆通片治疗。比较治疗4周后三组患者血清球蛋白、白蛋白/球蛋白比值、外周血白细胞计数等的差异。结果:空白组、对照组与实验组治疗前后血清球蛋白分别为(32.24±5.19)g/L与(31.96±5.27)g/L、(32.34±4.98)g/L与(28.06±5.57)g/L、(32.31±5.26)g/L与(27.66±5.86)g/L,治疗后对照组、实验组分别与空白组比较,差异有统计学意义(P<0.05)。三组治疗前后白蛋白/球蛋白比值分别为(1.014±0.206)与(1.029±0.170)、(1.008±0.162)与(1.248±0.244)、(1.011±0.195)与(1.276±0.275),治疗后对照组、实验组分别与空白组比较,差异有统计学意义(P<0.05)。三组治疗前后白细胞计数差异无统计学意义(P>0.05)。结论:复方胆通片能够降低肝硬化患者的血清球蛋白水平,作用与熊去氧胆酸胶囊接近。
Objective: To observe the effects of Compound Bile Tablets on the serum globulin and so on of patients with liver cirrhosis. Methods: 60 patients with liver cirrhosis were randomly divided into blank group, control group and experimental group, all patients received conventional anti-virus treatment, the control group was treated with Ursodeoxycholic Acid, the experimental group was added with Compound Bile Tablets. Compared the serum globulin, white/globulin ratio, peripheral white blood cell count and other differences in three groups after 4 weeks of treatment. Results: The serum globulin of blank group, control group and experimental group before and after treatment were (32.24±5.19) g/L and (31.96±5.27) g/L, (32.34±4.98) g/L and (28.06±5.57) g/L, (32.31±5.26) g/L and (27.66±5.86) g/L, comparison of control group, experimental group and blank group showed significant difference (P〈0.05). Three groups before and after treatment of white/globulin ratio were (1.014±0.206) and (1.029±0.170), (1.008±0.162) and (1.248±0.244), (1.011±0.195) and (1.276± 0.275), comparison of control group, experimental group and blank group showed significant difference (P〈0.05). Three groups of white blood cell count before and after treatment had no statistical difference (P〉0.05). Conclusion: Compound Bile Tablets can reduce the level of serum globulin, the role is close to Ursodeoxycholic Acid.
出处
《中国医药导报》
CAS
2010年第25期15-17,共3页
China Medical Herald
关键词
肝硬化
复方胆通片
熊去氧胆酸
内毒素血症
Liver cirrhosis
Compound Bile Tablets
Ursodeoxycholic Acid
Endotoxemia