主动免疫联合传统安胎治疗复发性流产的疗效观察

Efficacy of active immunization combined with conventional tocolysis in the treatment of recurrent spontaneous abortion

目的:探讨淋巴细胞主动免疫联合传统安胎治疗复发性流产的临床疗效。方法:将封闭抗体缺乏所致的复发性流产患者分为两组,一组采用淋巴细胞主动免疫加黄体酮及HCG传统安胎治疗为研究组,另一组采用传统安胎治疗(黄体酮加HCG)为对照组,观察两组疗效及妊娠结局。结果:研究组妊娠成功率为82.9%,对照组为56.8%,两组比较,有显著性差异(P<0.05)。结论:淋巴细胞主动免疫联合黄体酮及HCG治疗封闭抗体缺乏所致的复发性流产临床效果显著,是一种安全可靠的好方法。

Objective： To investigate the efficacy of immunotherapy with lymphocytes and progesterone plus HCG in treatment of women with recurrent spontaneous abortion. Methods： The women with recurrent spontaneous abortion caused by lack of blocking antibodies were divided into two groups, one group of active immunization with lymphocytes plus progesterone and HCG （research group）, another group of progesterone plus HCG （control group）, the efficacy and pregnancy outcome were observed. Results： The successful rate of pregnancy was 82.9% in the research group and was 56.8% in the control group. There was a significant difference between two groups （P〈0.05）. Conclusion： Lymphocyte active immunization and progesterone plus HCG for the recurrent spontaneous abortion with lack of blocking antibodies has a significant clinical effect, and it＇s safe and reliable.