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肝脏区域灌注三氧化二砷治疗晚期肝癌的疗效分析 被引量:3

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摘要 目的:探讨注射用三氧化二砷治疗晚期肝癌的临床疗效及生活质量改善。方法:选择我院2009年2月~2010年6月收治肝癌患者27例。27例患者均应用三氧化二砷在内的综合治疗手段,记录患者的缓解情况、影像学、生化指标及生活质量改善情况。结果:27例患者中6例有不同程度的缓解,17例疾病稳定,4例疾病进展死亡。其中14例患者在第一次接受治疗后癌痛症状明显减轻,2例患者的肿瘤标志物CA199明显降低。结论:三氧化二砷联合其他综合治疗手段治疗晚期肝癌患者的疗效明显,能够减轻患者痛苦,值得临床推广。
出处 《中国医药导报》 CAS 2010年第25期139-140,共2页 China Medical Herald
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  • 1张鹏,王树叶,胡龙虎,施福东,邱凤琴,洪珞珈,韩雪英,杨惠芬,宋颖昭,刘艳平,周晋,金镇敬.三氧化二砷注射液治疗72例急性早幼粒细胞白血病[J].中华血液学杂志,1996,17(2):58-60. 被引量:476
  • 2Zhang P, Wang SY, Hu LH, et al. Treatment of acute promyelocytic leukemia with intravenous arsenic trioxide [ J]. Zhonghua Xueyexue Zazhi ( Chin J Hematol) , 1996, 17 (2) :58.
  • 3Lan WX,San ZF, He JD. Treatment of relapsed acute promyelocytic leukemia with intravenous arsenic trioxide [ J]. Zhonghua Xueyexue Zazhi ( Chin J Hematol), 1999, 20 (2) : 109.
  • 4Chen GQ,Shi XG,Tang W,et al. Use of arsenic trioxide (As203 )in the treatment of acute promyelocytic leukemia(PAL) : As203 exerts dose - dependent dual effects on APL ceils [ J ]. Blood, 1997, 89(9):3345.
  • 5Chen GQ,Zhu J,Shi XG,et al. In vitro studies on cellular and molecular mechanisms of arsenic trioxide( As203 )in the treatment of acute promyglocytic leukemia: As203 induces NB4 cell apoptosis with downregulation of Bcl -2 expression and modulation of PML - RAR alpha/PML proteins [ J ]. Blood, 1996, 88 (3) : 1052.
  • 6Akao Y,Mizoguchi H,Kojima S,et al. Arsenic induces apoptosis in B -cell leukaemic cell lines in vitro: Activation of caspases and down - regulation of Bcl - 2 protein [ J ]. Br J Haematol,1998, 102(4): 1055.
  • 7Shen ZY, Tan LJ, Cai WJ, et al. Arsenic trioxide induces apoptosis of oesophageal carcinoma in vitro [ J ]. Int J Mol Med, 1999, 4(1) : 33.
  • 8Zhang TC,Cao EH,Li JF,et al. Induction of apoptosis and inhibition of human gastric cancer MGC - 803cell growth by arsenic trioxide [ J ]. Eur J Cancer, 1999, 35 (8) : 1258.
  • 9Livraghi T,Benedini V,Lazzaroni S,et al.Long term results of single session percutaneous ethanol injection in patients with large hepatocellular carcinoma.Cancer,1998,83(1):48-57
  • 10Seong J,Park HC,Han KH,et al.Local radiotherapy forunresectable hepatocellular carcinoma patients who failed with transcatheter arterial chemoembolization.Int J Radiat Oncol Biol Phys,2000,47(5):1331-1335

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