膀胱移行细胞癌伴前列腺腺癌的诊断与治疗（附6例报告）

Diagnosis and treatment of coincident vesical bladder transitional cell carcinoma and prostatic cancer （Report of 6cases）

目的提高膀胱移行细胞癌伴前列腺腺癌的诊治水平。方法对6例膀胱移行细胞癌伴前列腺腺癌患者的临床资料进行分析。结果6例中以膀胱肿瘤首诊4例，其中1例于术后19个月死于肿瘤转移，余3例随访22～58个月，平均35个月，1例无瘤生存，1例术后18个月出现肿瘤复发，另1例带瘤生存。以前列腺腺癌首诊的2例，分别随访20个月和46个月，均曾出现膀胱癌复发而行手术治疗，目前无瘤生存。结论血清PSA测定、直肠指诊、经直肠前列腺B超榆查＋活检及膀胱镜检查是诊断膀胱移行细胞癌伴前列腺腺癌的主要方法，其中治疗方案应根据膀胱癌的分期来确定，根治性膀胱前列腺切除是影响预后的重要因素。

Objective To study the diagnosis and treatment of coincident vesical bladder transitional cell carcinoma and prostatic cancer. Methods We retrospectively reviewed 6 patients with both bladder cancer and prostate cancer at our hospital between from July 2005 to March 2010. Results 4 patients were initially diagnosed bladder cancer, and 3 cases of them were followed up for 22 to 58 months （mean 35 months）. One case died of tumor metastasis 19 months after surgery, while one case was alive with recurrence and metastasis and the remainder one was alive without recurrence and metastasis. Two patients, initially diagnosed prostate cancer and followed up for 20 months and 46 months, respectively, were alive without recurrence and metastasis. Conclusions PSA detection together with rectal palpation, biopsy, transrectal ultrasonography and cystoscopy played the important role in the diagnosis of coincident vesical bladder transitional cell carcinoma and prostatic cancer. Radical cytoprostatectomy yields a better outcome.