海洛因依赖者的乙型肝炎和丙型肝炎感染

HBV and HCV Infections in Heroin Addicts

目的：了解海洛因依赖者的ＨＢＶ和ＨＣＶ感染情况，探讨其与感染有关的行为特征。方法：采用ＥＬＩＳＡ法检测了１５２例海洛因依赖者和５６例对照者的乙型肝炎和丙型肝炎感染情况，并调查了海洛因依赖者的成瘾史、不洁注射史、性伙伴情况等与肝炎传播有关的行为特征。发现海洛因依赖组与对照组的ＨＢＶ、ＨＣＶ感染率、总感染率、ＨＢＶ感染率、ＨＣＶ的感染率、ＨＢＶ和ＨＣＶ的重叠感染率依次分别为４６７％、２８３％、２７６％、９２％与１６７％、１１１％、５６％、０％。ＨＢＶ和ＨＣＶ的感染与海洛因依赖者的静脉注射、不洁注射史、成瘾时间及性别有关。提出在海洛因依赖者中预防ＨＢＶ、ＨＣＶ感染、减少药物滥用危害的重要性。

Objective:to investigate the prevalence of HBV and HCV infection among heroin addicts Method:using ELISA method to detect HBV Ab and HCV Ab in 152 heroin addicts and 56 normal controls At the same time,collecting the history of dependence,needle share,condition of sex partner and other behaviors related to the infection of hepatitis Result:the total prevalence of HBV or HCV infection in addicts and controls were 46 7% and 28 3% respectively The prevalence of HBV infection in the two groups were 27 6% and 9 2% respectively That of HCV infection was 16 7% and 11 0%,of HBV and HCV infection were 5 6% and 0% The infection of HBV or HCV in addicts correlated with i v injection,needle share,time of dependence and gender Conclusion:the prevention of hepatitis is important in heroin addicts to reduce the harm related to drug dependence