期刊文献+

新诊断2型糖尿病早期胰岛素强化治疗的临床观察

下载PDF
导出
摘要 我们选择86例新诊断未经治疗的2型糖尿病患者,年龄在18~56岁,随机分为胰岛素强化治疗组和口服降糖药治疗组,在治疗1个月、半年后比较两组患者的空腹血糖(FPG),餐后2h血糖(PPG),糖化血红蛋白(HbA1c),空腹胰岛素,餐后2h胰岛素水平,胰岛素分泌指数(HOMA-β)和胰岛素抵抗指数(HOMA-IR)。结果显示,胰岛素治疗组胰岛功能改善明显。有统计学差异。
作者 魏玉菊
出处 《中国医药指南》 2010年第26期89-90,共2页 Guide of China Medicine
  • 相关文献

参考文献2

二级参考文献18

  • 1[1]Butler AE,Janson J,Bonner-Weir S et al . Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes[J]. Diabetes,2003,52(1):102-110.
  • 2[2]Federici M,Hribal M,Perego L et al . High glucose causes apoptosis in cultured human pancreatic islets of Langerhans[J]. Diabetes,2001,50(6):1290-1301.
  • 3[3]Maedler D,Spinas GA,Dyntar D et al . Distinct effects of saturated and monounsaturated fatty acid on β-cell turnover and function[J]. Diabetes,2001,50(1):69-76.
  • 4[4]Maedler K,Oberholzer J,Bucher P et al . Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic β-cell turnover and function[J]. Diabetes,2003,52(3):726-733.
  • 5[5]Di Mario U,Dotta F. Beta-cell autoimmunity[J]. Diabete Metab Rev,1998,14(1):1-2.
  • 6[6]Zamzami N,Brenner C,Marzo I et al . Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins[J]. Oncogene,1998,16(17):2265-2282.
  • 7[7]Lin KT,Xue JY,Nomen M et al . Peroxynitrite-induced apoptosis in HL-60 cells[J]. J Biol Chem,1995,270(28):16487-16490.
  • 8[8]Betsholtz C,Christmansson L,Engstrom U et al . Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species[J]. FEBS Lett,1989,251(1-2):261-264.
  • 9[9]Janson J,Ashley RH,Harrison D et al . The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles[J]. Diabetes,1999,48(3):491-498.
  • 10[10]Ritzel RA,Butler PC. Replication increases beta-cell vulnerability to human islet amyloid polypeptide-induced apoptosis[J]. Diabetes,2003,52(7):1701-1708.

共引文献177

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部