氟哌噻吨美利曲辛对首发脑卒中患者卒中后抑郁的干预治疗

Observation on flupentixol melitracen to starting in stroke patients on the intervention of post-stroke depression

目的:探讨氟哌噻吨美利曲辛对首发脑卒中患者卒中后抑郁的干预治疗效果。方法:将2005年1月～2010年1月卒中后抑郁患者186例分为治疗组和对照组,治疗组96例,采用氟哌噻吨美利曲辛治疗,对照组90例采用阿米替林治疗,观察两组的临床疗效。结果:治疗组总有效率为96.87%,对照组为76.66%,两组总有效率比较,差异有统计学意义(P<0.05)。结论:应用氟哌噻吨美利曲辛治疗卒中后抑郁具有良好的抗抑郁效果,应用方便,毒副作用小,促进卒中后抑郁恢复,促进神经功能改善,显著提高了患者的生存质量。

Objective：To investigate flupentixol melitracen starting in stroke patients on the intervention of post-stroke depression treatment.Methods：Slected 186 patients in January 2005 to January 2010,who were divided into treatment group with 96 cases,flupentixol melitracen treatment,90 cases of the control group,treated with amitriptyline.Observed the clinical efficacy.Results：The total effective rate of treatment group was 96.87%,the control group was 76.66%,there was significant difference between the two groups（P 0.05）.Conclusion：Flupentixol melitracen treatment of the post stroke depression has a good antidepressant effect,and is convenient,has toxic side effects,and can promote the recovery of post-stroke depression,promote improvement in neurological function,significantly improves the quality of lires of patients.