输注依托咪酯治疗库欣综合征危象

1例17岁、55kg，疑似库欣综合征的女孩被送到一所大学医院的内分泌科以明确病因。患者接受了3天的口服酮康唑治疗，但因肝功能检验指标的快速、大幅升高而改用静脉注射依托咪酯治疗。这种静脉注射依托咪酯的方法可以降低血清皮质醇水平，使得患者能耐受肾上腺切除手术。

A 17-year-old, 55 kg girl was referred to the endocrinology department of a university hospital to determine the etiology of suspected Cushing＇s syndrome. The patient was treated with oral ketoconazole for 3 days, but a rapid and severe elevation in her liver function test results led to selection of IV etomidate as a therapeutic option. This approach led to decreasing levels of serum cortisol, and the patient was able to tolerate surgical adrenalectomy.