亚碲酸钠催化无溶剂Knoevenagel反应的研究

Knoevenagel Condensation Catalyzed by Na_2TeO_3 Using Grinding Method under Solvent-free Condition

以亚碲酸钠为催化剂,采用研磨方法,芳醛与活泼亚甲基化合物能在室温条件下进行Knoevenagel缩合反应。实验结果表明,亚碲酸钠对芳香醛与活泼亚甲基化合物的Knoevenagel缩合反应具有良好的催化效果。该法具有反应条件温和,实验操作简单,后处理方便,催化剂能够循环使用,对环境友好等优点。

Knoevenagel condensation of various aromatic aldehydes with active methylene compounds catalyzed by sodium tellurite by grinding at room temperature under solvent-free condition was described.The experimental results showed that the reported protocol had the merits of mild reactions,convenient experimental and work-up procedure,excellent yields,recycling of catalysis and environmental friendly.