摘要
本文综述了少突胶质细胞相关基因SOX10,NRG1,Nogo等对精神分裂症的影响,影像学动物学发现了少突胶质细胞与精神分裂症的关系,提出了少突胶质细胞是精神分裂症发病的关键之一,并可作为治疗靶点。
出处
《国际精神病学杂志》
2010年第3期151-154,共4页
Journal Of International Psychiatry
参考文献13
-
1Aston C, Jiang L, Sokolov BP. Microarray analysis of postmortem temporal cortex from patients with schizophrenia. J Neurosci Res. 2004 ; 77 : 858 - 866.
-
2Davis KL, Stewart DG, Friedman JI, et al. White matter changes in schizophrenia: evidence for myelin-related dysfunction. Arch Gen Psychiatry, 2003 ; 60. 443 - 456.
-
3Stolt CC, Rehberg S, Ader M, et al. Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002; 16: 165 - 170.
-
4Tkachev D, Mimmack ML, Ryan MM, et al. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet, 2003 ; 362 : 798 - 805.
-
5Qin W, Gao J, Xing Q, et al. A family-based association study of PLP1 and schizophrenia. Neurosci Lett. 2005 ; 375 : 207 - 210.
-
6Galiano MR, Andrieux A, Deloulme JC, et al. Myelin basic protein functions as a microtubule stabilizing protein in differentiated oligodendrocytes. J Neurosci Res. 2006; 84: 534 - 541.
-
7Tan EC, Chong SA, Wang H, et al. Genderspecific association of insertion/deletion polymorphisms in the nogo gene and chronic schizophrenia. Brain Res Mol Brain Res. 2005; 139:212-216.
-
8Novak G, Tallerico T. Nogo A, B and C expression in schizophrenia, depression and bipolar frontal cortex, and correlation of Nogo expression with CAA/TATC polymorphism in 30- UTR. Brain Res. 2006; 1120:161 -171.
-
9Yang YF, Qin W, Shugart YY, et al. Possible association of the MAG locus with schizophrenia in a Chinese Han cohort of family trios. Schizophr Res. 2005; 75:11 -19.
-
10Qu M, Yue W, Tang F, et al. Polymorphisms of Transferrin gene are associated with schizophrenia in Chinese Han population. J Psychiatr Res. 2008 ; 42 ( 11 ) : 877 - 83.
同被引文献26
-
1Segal D,Koschnick JR,Slegers LH. Oligodendrocyte pathophysiology:a new view of schizophrenia[J].The international journal of neuropsychopharmacology/official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP),2007,(04):503-511.
-
2Voineskos AN,Felsky D,Kovacevic N. Oligodendrocyte genes,white matter tract integrity,and cognition in schizophrenia[J].{H}CEREBRAL CORTEX,2013,(09):2044-2057.
-
3Carter CJ. Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation,oxidative stress and oligodendrocyte viability[J].{H}Schizophrenia Research,2006,(1-3):1-14.
-
4Zhang R,He J,Zhu S. Myelination deficit in a phencyclidineinduced neurodevelopmental model of schizophrenia[J].{H}Brain Research,2012.136-143.
-
5Kang C,Yang X,Xu X. Association study of neuregulin 1 gene polymorphisms with auditory P300 in schizophrenia[J].American journal of medical genetics Part B Neuropsychiatric genetics:the official publication of the International Society of Psychiatric Genetics,2012,(04):422-428.
-
6Law A J,Lipska BK,Weickert CS. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease[J].{H}Proceedings of the National Academy of Sciences(USA),2006,(17):6747-6752.
-
7Roy K,Murtie J C,El-khodor B F. Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function,a potential mechanism for neuropsychiatric disorders[J].{H}Proceedings of the National Academy of Sciences(USA),2007,(19):8131-8136.
-
8Fazzari P,Paternain AV,Valiente M. Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling[J].{H}NATURE,2010,(7293):1376-1380.
-
9Maeno N,Takahashi N,Saito S. Association of SOX10 with schizophrenia in the Japanese population[J].{H}PSYCHIATRIC GENETICS,2007,(04):227-231.
-
10Li W,Wang X,Zhao J. Association study of myelin transcription factor 1-1ikepolymorphisms with schizophrenia in Han Chinese population[J].Genes brain and behavior,2012,(01):87-93.
-
1汪诚信教授代表主审和读者在《啮齿动物学》首发式上的发言[J].中华卫生杀虫药械,2008,14(1):79-79.
-
2苏晖,施慎逊.5-HT_(1A)受体对抑郁焦虑行为的调节作用及其机制[J].上海交通大学学报（医学版）,2015,35(9):1403-1406. 被引量：17
-
3洪丽丹,刘燕,刘明明.抑郁症或可“闻乐而愈”[J].名医,2012(9):12-15.
-
4Nonaka D,Chiriboga L,Rubin B P,杨小兵(摘译),黄文斌(审校).SOX10：一种光谱的神经鞘细胞和黑色素细胞的标记物[J].临床与实验病理学杂志,2008,24(6):695-695.
-
5卢雅彬,杨印祥,汪兆艳,栾佐.适于人源少突胶质前体细胞长期体外扩增的较经济的培养方法[J].中华实用儿科临床杂志,2014,29(19):1492-1496.
-
6Q95 动物学[J].中国生物学文摘,2005,19(1):139-142.
-
7GABRIELA FRAGOSO,JEFFERY D.HAINES,JANICE ROBERSTON,LILIANA PEDRAZA,WALTER E.MUSHYNSKI,GUILLERMINA ALMAZAN.p38 Mitogen-Activated Protein Kinase Is Required for Central Nervous System Myelination[J].神经损伤与功能重建,2008,3(2):99-108.
-
8张颖,陈朝,陈宇霞,黄世敬.知母及含知母复方的抗抑郁研究现状[J].环球中医药,2016,9(3):377-380. 被引量：11
-
9王斌全,赵晓云.罗杰斯与她的护理理论[J].护理研究（中旬版）,2008,22(2).
-
10JUDITH M LYTLE,RAMESH CHITTAJALLU,JEAN R WRATHALL,VITTORIO GALLO.NG2 Cell Response in the CNP-EGFP Mouse After Contusive Spinal Cord Injury[J].神经损伤与功能重建,2009,4(1):33-47. 被引量：7
