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强迫障碍的脑功能影像学研究 被引量：1

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摘要 大量脑功能影像学研究证实强迫障碍患者的眶额-基底节-丘脑环路存在异常。本文就近年来强迫障碍的功能影像学研究做一综述。
作者 罗佳 郭志华 李占江
机构地区 首都医科大学附属北京安定医院
出处 《国际精神病学杂志》 2010年第3期157-159,共3页 Journal Of International Psychiatry
基金 北京市自然科学基金(项目编号7082046)
关键词 强迫障碍 眶额-基底节-丘脑环路 脑功能影像学
分类号 R749 [医药卫生—神经病学与精神病学]
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参考文献16

  • 1Kwon JS, Kim J J, Lee DW, et al. Neural correlates of clinical symptoms and cognitive dysfunctions in obsessive-compulsive disorder. Psychiatry Res : Neuroimaging, 2003 ; 122 : 37 - 47.
  • 2Adler CM, McDonough-Ryan P, Sac WK, et al. fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder. J Psychiatr Res. 2000; 30:317-324.
  • 3Alptekin K, Degirmenci B, Kivircik B, et al. Tc-99m HMPAO brain perfusion SPECT in drug-free obsessive-compulsive patients without depression. Psychiatry Res: Neuroimaging, 2001; 107 (1): 51-56.
  • 4陈晓丽,谢敬霞,韩鸿宾,张伯全.强迫症症状诱发磁共振灌注成像及定量分析[J].中国医学影像技术,2004,20(3):394-396. 被引量：3
  • 5Ursu S, Carter CS. An initial investigation of the orbitofrontal cortex hyperactivity in obsessive-compulsive disorder: Exaggerated representations of anticipated aversive events. Neuropsychologia, 2009 ; 47 : 2145 - 2148.
  • 6Yamanishi T, Nakaaki S, Omori IM, et al. Changes after behavior therapy among responsive and nonresponsive patients with obsessivecompulsive disorder. Psychiatry Res: Neuroimaging, 2009 ; 172 (3) : 242 - 250.
  • 7Jang JH, Kwon JS, Jang DP, et al. A Proton MRSI Study of Brain N-Acetylaspartate Level After 12 Weeks of Citalopram Treatment in Drug-Nalve Patients With Obsessive-Compulsive Disorder. Am J Psychiatry, 2006; 163:1202 -1207.
  • 8Yucel M, Harrison B J, Wood SJ, et al. Functional and Biochemical Alterations of the Medial Frontal Cortex in Obsessive-Compulsive Disorder. Arch Gen Psychiatry, 2007; 64 (8) : 946 - 955.
  • 9Nakao T, Nakagawa A, Yoshiura T, et al. A functional MR1 comparison of patients with obsessive-compulsive disorder and normal controls during a Chinese character Stroop task. Psychiatry Res: Neuroimaging, 2005; 139:101-114.
  • 10Nabeyama M, Nakagawa A, Yoshiura T, et al. Functional MRI study of brain activation alterations in patients with obsessive-compulsive disorder after symptom improvement. Psychiatry Res : Neuroimaging, 2008 ; 163 : 236 - 247.

二级参考文献7

  • 1[1]Chang L, Ernst T, Speck O, et al. Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users[J]. Psychiatry Research: Neuroimaging, 2002,114(2):65-79.
  • 2[2]Rauch SL, Jenike MA, Alpert NM, et al. Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography[J]. Archives of General Psychiatry,1994,51(1):62-70.
  • 3[3]Alptekin K, Degirmenci B, Kivircik B, et al. Tc-99m HMPAO brain perfusion SPECT in drug-free obsessive-compulsive patients without depression[J]. Psychiatry Research: Neuroimaging,2001,107(1):51-56.
  • 4[4]Lacerda AL, Dalgalarrondo P, Caetano D, et al. Elevated thalamic and prefrontal regional cerebral blood flow in obsessive-compulsive disorder: a SPECT study[J]. Psychiatry Research: Neuroimaging,2003, 123(2):125-134.
  • 5[5]Saxena S, Brody AL, Schwartz JM, et al. Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder[J]. Br J Psychiatry, 1998,173(Suppl):26-37.
  • 6[6]Karayiorgou M, Sobin C, Blundell ML, et al. Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder[J]. Biological Psychiatry,1999, 45(9):1178-1189.
  • 7[7]Adler CM, McDonough-Ryan P, Sax KW, et al. fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder[J]. Journal of Psychiatric Research, 2000,34(4-5):317-324.

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国际精神病学杂志
2010年 第3期

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