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45例系统性红斑狼疮临床及病理分析 被引量:3

Clinical and Pathologic Analysis in 45 Patients with Systemic Lupus Erythematosus
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摘要 目的探讨系统性红斑狼疮(SLE)的临床及组织病理学特点。方法回顾分析天津市长征医院2003年1月—2007年2月住院的SLE患者临床表现及组织病理学特点。结果发病高峰为10~40岁,以女性为多;临床表现分析显示,蝶形红斑、光敏、关节痛、脱发最为常见症状,其次为雷诺现象及发热;实验室指标分析显示,ANA、ENA、ds-DNA、免疫球蛋白/补体异常阳性率较高;男性组与女性组比较临床表现及实验室指标均有差异;SLE组织病理学特征变化多样,狼疮带试验在SLE的诊断中十分重要。结论 SLE患者临床表现及组织病理学表现多样。 Objective To analyze the clinical and pathologic features of systemic lupus erythematosus(SLE). Methods 45 cases of SLE patients from Tianjin Changzheng hospital were collected and analyzed retrospectively. Results The high prevalence clinical feature was butterfly facial erythema, photosensitive, arthralgia, alopecia. The second was Raynaud's phenomenon and fever. The immunologic features were ANA, ENA, ds-DNA and immunoglobulin/serum complement. There was difference between male group and female group. Lupus band test(LBT) is specific for the diagnosis of SLE. Conclusion The clinical and pathologic features of SLE is multiple.
作者 唐莉 王红梅
机构地区 天津市长征医院
出处 《中国中西医结合皮肤性病学杂志》 CAS 2010年第4期222-224,共3页 Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine
关键词 系统性红斑狼疮 临床表现 实验室指标 组织病理 systemic lupus erythematosus clinical features immunologic features pathologic features
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参考文献7

  • 1高辉,樊均明.108例系统性红斑狼疮临床分析[J].华西医学,2005,20(3):513-514. 被引量:3
  • 2李永红,李钟洙,林维嘉,吴泳.系统性红斑狼疮165例临床分析[J].中国麻风皮肤病杂志,2007,23(5):374-375. 被引量:1
  • 3Tsao BP.An update on genetic studies of systemic lupus erythematosus[J].Curr Rheumatol Rep,2002,4:359-367.
  • 4HO A,Magder LS,Barr SG,et al.Decreases in anti-doublestranded DNA levels are associated with concurrent flares in patients with systemic lupus erythematosus[J].Arthritis Rheum,2001,44:2342-2349.
  • 5HO A,Barr SG,Magder IS,et al.A deerease in complement is associated with increased renal and hematologic activity in patients with systemic lupus erythematosus[J].Arthritis Rheum,2001,44:2350-2357.
  • 6朱学俊,孙建方译.皮肤病理学与临床的联系[M].北京:北京医学大学出版社,2007:1757.
  • 7唐书谦,钟白玉,叶庆佾,郝飞,陈艳.皮肤狼疮带试验与临床分析[J].中国皮肤性病学杂志,2004,18(5):279-280. 被引量:3

二级参考文献15

  • 1崔惠敏,张秋生,菅宏蕴,吴素红,陈小红,刘冠贤.老年性系统性红斑狼疮的临床特点及预后[J].中国中西医结合肾病杂志,2005,6(7):386-388. 被引量:5
  • 2叶任高,谢春.要重视对狼疮性肾炎的研究[J].中华内科杂志,1997,36(2):75-76. 被引量:44
  • 3陈灏珠.实用内科学[M](第10版)[M].北京:人民卫生出版社,1997.835-838.
  • 4Huong DL,Papo T,Beaufils H, et al.Renal involvement in systemic lupus erythematosus[J].Medicine(Baltimore)1999,78:148-66.
  • 5Uramoto KM,Michet CJ,Thumboo J,et al.Trends in the incidence and mortality of systemic lupus erythematosus,1950-1992[J].Arthritis Rheum 1999,42:46-50.
  • 6Kuiper-Geertsma,Dudy G;Derksen, Ronald H.W.M.Newer Drugs for the Treatment of Lupus Nephritis[J].Drugs,2003,63(2):167-180.
  • 7Bansal VK,Beto JA.Treatment of lupus nephritis:a meta analysis of clinical trials[J].Am J Kidney Dis 1997.29:193-9.
  • 8Zecevic.Significance of deposits of immunoglobulins GAM and c3 complement component in the basal membrane zone of clinically unchanged skin for the diagnosis and evaluation of systemic lupus erythematosus activity[J].Vojnosanit Pregl,2001,58(4):359-374.
  • 9Cardinali C,Caproni M,Fabbri P,et al.The utility of the lupus band test on sun-protected non-lesional skin for the diagnosis of systemic lupus erythematosus[J].Clin Exp Rheumatol,1999,17(4):427-432.
  • 10Boey ML,Peebles CI,Tsay G,et al.Clinical and autoantibody correlations in Oerientals with SLE.Ann Rheum Dis 1988;47:918.

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