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寻常性银屑病皮损Ki-67抗原表达及意义 被引量：1

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摘要 目的探讨Ki-67抗原在寻常性银屑病皮损中的表达以及皮损严重程度的关系。方法应用免疫组织化学方法检测Ki-67抗原的表达,并与银屑病严重程度积分(PASI)进行相关性分析。结果 Ki-67抗原在寻常性银屑病皮损表达强度明显增高(与外观正常皮比较,P<0.05),主要表达在细胞生发层和分裂旺盛的组织;它的表达与PASI呈正相关(r=0.770,P<0.01)。结论 Ki-67抗原在寻常性银屑病皮损中的表达明显升高,在一定程度上和银屑病严重程度相关。
作者 杨文犀 李桂珍 张理涛
机构地区 天津市南开医院 天津市长征医院
出处 《中国中西医结合皮肤性病学杂志》 CAS 2010年第4期228-229,共2页 Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine
关键词 银屑病 寻常性 KI-67抗原 表达
分类号 R758.63 [医药卫生—皮肤病学与性病学]
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中国中西医结合皮肤性病学杂志
2010年 第4期

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