东莞市2008年儿童麻疹疫苗初免成功率监测

Surveillance on immune successful rate of measles vaccine in infants of Dongguan in 2008

目的:监测评价麻疹疫苗免疫效果,判断免疫成功率及保护率。方法:取8月龄儿童在接种麻疹疫苗前和完成基础免疫后1个月的血清标本各50份,用酶联免疫吸咐法检测麻疹IgG抗体,抗体滴度≥1:200判断为阳性,抗体滴度≥1:800则达到保护水平。结果:免疫前阳性率为0,免疫后阳性率为100%,免疫成功率为100%。有49份标本免疫后IgG抗体滴度≥1:800,达到了保护水平。不同性别的保护水平无显著性差别。结论:免疫成功率达到要求的标准(≥85%),98%达到保护水平。

Objective：To survey and evaluate the effect of immunization of measles vaccine and judge the immune successful rate and protective rate.Methods：To collect 50 preimmunization one month post-immunization serum of 8 months aged infants respectively and detect the IgG antibodies anainst measles by ELISA.The antibody titer≥1：200 was regarded as positive,≥1：800 reached to the protective level.Results：The positive rate of preimmunization was zero,the positive rate of post-immunization was 100%,the immune successful rate of measles vaccine was 100%,the IgG antibody titer of 49 infants were≥1：800,it reached to the protective level.There were no significant difference between different gender on protective level.Conclusion：The immune successful rate reach to the standard（≥85%）,98% of the infants reach to the protective level.There are no significant difference between different geder.