摘要
目的探讨肌萎缩侧索硬化症(ALS)的肌电图及病理诊断特点。方法对62例ALS患者的临床资料、肌电生理改变及肌肉活检病理特点进行了回顾性分析。结果 62例患者肢体肌电检查均有异常表现,其中54例胸段棘旁肌肌电图检查有异常表现,胸锁乳突肌肌电图检查有异常表现者52例。肌肉活检62例患者活检组织均以小群性萎缩为主,3例患者病理切片局部可见大群性萎缩。48例可见同型肌纤维群化,13例出现靶纤维。结论肌电图检查和肌肉活检对ALS诊断有重要的意义,两者相结合更加可靠。
【Objective】To study the clinical and pathological features of amyotrophic lateral sclerosis (ALS).【Methods】The general clinical data ,the changes of electromyogram and the pathological features of 62 ALS patients were retrospectively analyzed.【Results】Abnormal waves were found in muscles of limbs of all 62 ALS patients and in thoracic paraspinal muscles of 54 patients.Abnormal waves were found in sternocleidomastoid muscle from 52 of 62 ALS patients.Muscular biopsy showed obvious pathological changes.All 62 cases were characterized by small grouping atroghy and large grouping atroghy appeared in 3 cases.48 cases were associated with type grouping and 13 cases were associated with target fibers.【Conclusions】Electromyogram and neural and muscular biopsy are both important for the diagnosis of ALS.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2010年第15期2323-2325,共3页
China Journal of Modern Medicine
关键词
肌萎缩侧索硬化
肌电图
病理学
amyotrophic lateral sclerosis
electromyogram
pathology