普鲁卡因静脉封闭治疗成人带状疱疹短期疗效观察

The Efficacy and Safety of Procaine in Vein in Treatment on Herpes Zoster

目的:了解普鲁卡因治疗带状疱疹的疗效及安全性。方法:治疗组加普鲁卡因240mg,1次/d,缓慢静脉滴注;治疗组及对照组均予更昔洛韦0.25,2次/d,静脉滴注;1、2、3、5、7d观察症状、体征,两组疗程均为7d。结果:治疗组与对照组总有效率分别是85.7%、66.4%,差异有显著性(P<0.01),治疗组止痛效果明显优于对照组(P<0.01)。结论:普鲁卡因治疗重症带状疱疹及以疼痛为主的带状疱疹是一个安全、高效的药物。

Objective：To explore the effect and security for herpes zoster treated with procaine.Methods：Treatment group using procaine 0.24 qd in vein slowly,treatment group and control group using ganciclovir 0.25 bid in vein together.Symptom and sign were observed at 1,2,3,5,7days after treatment.The course therapy was both 7 days.Results：Total effective ratio of treatment group and control group were 85.7%,66.4% respectively,and had significant variance（P 0.01）.especially campared with that of control group,the effict of procaine in relieving pain was quick and obvious（P 0.01）,and few abverse reaction.Conclusions：Procaine is a broad spectrum anti-virus drug,high effect,security,especially treating for heavy herpes zoster and herpes zoster with neuralgia.