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依据子宫内膜厚度治疗青春期功能失调性子宫出血的临床体会 被引量:6

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摘要 目的 应用彩超监测青春期功能失调性子宫出血(功血)患者子宫内膜厚度,指导临床对不同的子宫内膜厚度选用正确的治疗方法.方法 青春期功血患者268例,使用彩超诊断仪经肛门检测子宫内膜厚度,依据子宫内膜的厚度分为三组:子宫内膜厚度<0.5 cm组(75例)、子宫内膜厚度0.5~1.0 cm组(100例)、子宫内膜厚度>1.0 cm组(93例),每组再按患者自愿原则分为三个亚组,分别口服戊酸雌二醇(补佳乐)、炔诺酮(妇康片)、去氧孕烯炔雌醇(妈富隆),观察各组服药后快速控制出血、快速止血情况.结果 子宫内膜厚度<0.5cm组中,补佳乐亚组快速控制出血率、快速止血率[78.26%(18/23)、52.17%(12/23)]均高于妇康片亚组[37.50%(9/24)、25.00%(6/24)]和妈富隆亚组[21.43%(6/28)、25.00%(7/28)](P<0.05).子宫内膜厚度0.5~1.0cm组中,三个亚组快速控制出血率、快速止血率两两比较差异均无统计学意义(P>0.05).子宫内膜厚度>1.0cm组中,妇康片亚组快速控制出血率、快速止血率[76.67%(23/30)、56.67%(17/30)]均高于补佳乐亚组[31.43%(11/35)、25.71%(9/35)]和妈富隆亚组[32.14%(9/28)、28.57%(8/28)](P<0.05).三组患者中有4例出现轻微的恶心等胃肠道反应,没有因为不良反应而停止治疗者.结论 经肛门彩超检测子宫内膜厚度,不需要充盈膀胱,操作简单.依据子宫内膜厚度应用药物治疗青春期功血,效果显著,避免了以往治疗的盲目性,值得临床借鉴.
出处 《中国医师进修杂志》 2010年第24期37-38,共2页 Chinese Journal of Postgraduates of Medicine
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