期刊文献+

线粒体、Bcl-2s与凋亡 被引量:6

下载PDF
导出
摘要 线粒体、Bcl=2s与凋亡有重要的联系。线粒体在死亡信号的诱导下,跨膜电位(m)下降,通透性转变(PT)是细胞凋亡的早期特征。位于线粒体外膜的Bcl-2/Bcl-XL一方面可能形成离子通道,调节PT形成和抑制m的下降,另一方面通过与其他调亡相关蛋白的反应,抑制凋亡相关蛋白酶Caspases的活化而阻止凋亡的发生。
作者 刘卫军
出处 《国外医学(生理病理科学与临床分册)》 1999年第2期113-115,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
  • 相关文献

同被引文献43

  • 1[1]Tham K M,Moon C D. Apoptosis in cultures induced by infectious bursal disease virus following in vitro infection[J]. Avian Disease,1996,40:109~113
  • 2[2]Vasconcelos A C, Lam K M. Apoptosis induced by infectious bursal disease virus[J]. J Virol,1994,75:1803~1806
  • 3[3]Vasconcelos A C, Lam K M. Apoptosis in chicken embryos induced by infectious bursal disease virus[J]. Journal of Comparative Pathology,1995,112:327~338
  • 4[4]Fernandez-arias A S, Rodriguez J F. The major antigenic protein of infectious bursal disease virus, VP2, is an apoptotic inducer[J]. J Virol,1997,71(10):8014~8018
  • 5[7]Rien I E W, Reutelingsperger C P M, Holdaway K M. The use of annexin-V and TUNEL to monitor the progression of apoptosis in plants[J]. Cytometry, 1997, 29:28
  • 6[8]Ormerod M G. The study of apoptotic cells by flow cytometry[J]. Leukamia, 1998,12:1013~1025
  • 7Deutscher S, Rockette H E, Krishnaswami V. Evaluation of habitual excessive alcohol consumption on myocardial infarction risk in coronary disease patientsp [ J ]. Am Heart J, 1984,108:988-993.
  • 8Polimeni P I, Otten M D, Hoeschen L E. In vivo effects of ethanol on the rat myocardium: evidence for a reversible,non-specific increase of sarcolemmal permeability[J]. J Mol Cell Cardiol, 1983,15: 113-122.
  • 9Noren G R, Staley N A, Einzig S, et al. Alcohol-induced congestive cardiomyopathy: an animal model[ J]. Cardiovase Res, 1983,17: 81-87.
  • 10Johannes A G R. Histology:A Text and Atlas[M]. UK:Oxford University Press, 1974. 234-244.

引证文献6

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部