老年幽门螺杆菌相关性胃炎的治疗

The treatment of senile pyloric helicobacter pylori pertinence gastritis

目的：研究老年幽门螺旋杆菌（Helicobacterpylori，Hp）相关性胃炎的治疗方法。方法：将91例经胄镜及病理证实为Hp阳性者随机分为3组，采用羟氨苄青霉素分别与呋喃唑酮、庆大霉素、甲硝唑配伍。结果：组Ⅰ（加服呋喃唑酮）的有效率和Hp根除率优于组Ⅱ（加服庆大霉素）（P＜0．05）．组Ⅱ的有效率和Hp根除率优于组Ⅲ（加服甲硝唑）（P＜0．05）．结论：抗生素短疗程，联合治疗方案可提高Hp的根除率和临床症状改善率，其中以羟氨苄青霉素并用呋喃唑酮组疗效最佳。

Objective; to study the therapy method for senile heicobacter pylori (Hp) related gastritis. Method: Ninty one patients were divided into 3 groups at random, Hp of whom was positive using astroscopy and pathological examination. The 3 groups were given phydroxyampicillin with furazolidone or gentamycin or metronidazole respectiveIy. Resultf:The effective ratio and Hp extirpation ratio of Ⅰ Group 1 (with furazolidone) were bigher than those of Group Ⅱ (with gentamycin) (P<0.05). The effective ratio and Hp extirpation ratio of Ⅱ Group Ⅱ were than those Group Ⅲ (with metronidazole) (P<0.05). Conclusion: The therapy duration of antibiotic is shofL The combinative medication shows higher Hp extirpation ratio and improvement ratio of clinical Symptom, especially, the curative effect is best in using phydroxyampicillin together with furazolidone.