环丙沙星与甲硝唑对手术切口封闭作用的临床分析

Effects of ciprofloxacin and metronidazole on incision sealing

目的：研究环丙沙星与甲硝唑对手术切口封闭作用的差异和患者腹壁脂肪厚度对切口感染的影响．方法：386例急性化脓性阑尾炎穿孔、腹膜炎患者进行随机分组，分别用2％环丙沙星注射液及0．2％甲硝唑注射液进行切口封闭，用校正X2检验两组P值，并按腹壁脂肪厚度分成两组，用校正X2统计量检验两组P值。结果两个P值分别为P＜0．05和P＜0．01．结论：用环丙沙星封闭急性化脓性阑尾炎穿孔、腹膜炎手术切口比甲硝唑更有效，并且证明切口感染与腹壁脂肪厚度有密切关系，腹壁脂肪越厚感染的概率越大。

Objective: To study the difference in the effects of ciprofloxacin and metronidazole on incision scaling and the influence of patient's belly fat thickness on incision infection. Methods: 386 cases of acute purulent appendiceal perforation and peritonitis were grouped at random and given 2% ciprofloxacin and 0.2% metronidazole injection liquids, respectively,with correction X2 test for pvalue (P＜0.05).They were divided into two groups according to their belly fat thickness, with correction X2 test for pvalue (P＜0.01). Conclusion: It is better to seal incision of acute purulent appendiceal perforation and peritonitis with ciprofloxacin than with Metronidazole. Further more,There is close relationship between incision infection and belly fat thickness.