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离子通道与神经病理性疼痛 被引量：1

Ion channel and neuropathic pain
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摘要 神经病理性疼痛是由神经系统损伤所致的一种慢性疼痛，发病机制复杂。已经证实异位放电是痛觉异常的电生理学基础，并且离子通道改变是形成异常放电的主要原因。就现有文献报道的感觉神经元中一些重要离子通道在神经病理性疼痛中的变化作一简单综述。 Neuropathic pain is a chronic pain caused by nervous system lesions, which pathogenesis is complex. It has been shown that ectonic discharge is the electrophysiologic base of allodynia, and the change of ion channels is a major cause of ectonic discharge. This review focuses on changes of some important ion channels in neuropathic pain reported in available literature.
作者 吴焕兵 王学仁
机构地区 武警湖北省总队医院医务处 华中科技大学同济医学院附属同济医院麻醉学教研室
出处 《国际麻醉学与复苏杂志》 CAS 2010年第4期356-359,共4页 International Journal of Anesthesiology and Resuscitation
关键词 神经病理性疼痛 离子通道 Neuropathic pain Ion channels
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献23

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二级参考文献39

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国际麻醉学与复苏杂志
2010年 第4期

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