两种气道湿化方法对呼吸机相关性肺炎发生率的影响

Influence of airway humidification on the incidence of ventilator-associated pneumonia

目的探讨两种气道湿化法对呼吸机相关性肺炎发生率的影响。方法选择2009年1-12月行机械通气7-10d的患者25例为试验组,用湿热交换器+微泵持续气道湿化法进行气道湿化;选择2008年1-12月行机械通气7-10d的患者20例为对照组,用传统的加热湿化器进行气道湿化。比较两组的体温、血白细胞数、中性粒细胞百分比、痰培养结果、X线胸片结果、痰痂形成例数。结果试验组4例(16%)发生呼吸机相关性肺炎,对照组9例(45%)发生呼吸机相关性肺炎,差异有统计学意义(χ2=4.55,P<0.05)。结论湿热交换器+微泵持续气道湿化法,预防呼吸机相关性肺炎效果较好。

Objective To evaluate the effect of modified airway humidification on the incidence of ventilator-associated pneumonia.Methods Heat and moisture exchanger （HME） integrated with continuous airway humidification by micro-pump and traditional method of were provided for the 25 patients from January to December 2009 in the experimental group,and airway humidification with heating humidifier（HH） for 20 patients from January to December 2008 in the control group,respectively.The patients＇ body temperature,blood leukocyte count,neutrophil count,sputum culture results,X-ray results,the incidence of sputum callus formation were recorded and compared between the two groups.Results The incidence of ventilator-associated pneumonia was significantly lower in the experimental group than that in the control group（16% vs.45%, χ^2=4.55, P〈0.05）.Conclusion HME integrated with continuous airway humidification by micro-pump is more effective to prevent ventilator-associated pneumonia.