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胸液Cyfra21-1测定对结核性和癌性胸腔积液鉴别诊断的价值

The value of CYFRA 211 in pleural luid for the differential diagnosis of malignant and tuberculous pleural effusion.
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摘要 目的为评价Cyfra21-1对癌性胸液的诊断价值。方法采用ELISA方法测定30例结核性胸液和30例癌性胸液患者胸液中的Cyfra21-1含量。结果Cyfra21-1临界值为≤14.23ng/ml。当特异性为90%时,诊断癌性胸液的敏感性73.33%。结论胸液Cyfra21-1的检测对癌性胸腔积液的鉴别诊断有着重要的意义。 Objective To investigate whether cytokeratin solution 19 fragment CYFRA211 is useful for the differential diagnosis of malignant and benign pleural effusions. Methods The concentration of Cyfra211 in pleural effusion from 30 patients with tuberculous pleurisy and 30 patients with malignant pleurisy were measured by ELISA. Results When the concentrations of CYFRA 211 in pleural fluid was 1423ng/ml.the sensitivity of pleural fluid CYFRA 211 for diagnosis of malignant pleural effusion was 7333%,when the specificity was 90%. Conclusion We conclude that the measurement of CYFRR 211 in pleural effusion may be useful for the differential diagnosis of malignant and tuberculous pleural effusions.
机构地区 海南省人民医院
出处 《临床内科杂志》 CAS 1999年第1期23-24,共2页 Journal of Clinical Internal Medicine
关键词 CYFRA21-1 肺结核 肺肿瘤 胸腔积液 测定 pleural effusionCYFRA211Lung tuberculousLung neoplasms
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  • 1郭华北,国外医学临床生物化学与检验学分册,1995年,16卷,1期,8页
  • 2韩葆惠,上海医科大学学报,1994年,21卷,187页

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