重症肌无力合并低T_3综合征25例临床分析

Myasthenia gravis accompanying low T_3 syndrome:Analysis of 25 cases

目的重症肌无力合并低T3综合征的主要原因分析。方法对我院重症肌无力(Myasthenia Gravis,MG)中25例重症肌无力合并低T3综合征患者及40例MG但甲功七项均正常作对照分析。结果25例合并低T3综合征中眼肌型的主要因素是年龄。中度全身型患者用糖皮质激素持续治疗和长期进食困难、营养消耗是伴发低T3综合征的重要因素。结论重症肌无力累及肌肉部位不同,合并低T3综合征原因不同。

Objective To analyze the main causes of myasthenia gravis（MG） accompanying low T3 syndrome.Methods Twenty-five MG patients accompanying low T3 syndrome and 40 MG patients with normal thyroid hormone were enrolled in this study.Their thyroid hormone levels including APOAb,TT3,TT4,FT3,FT4,and TSH were measured.Results The main factor for ocular MG accompanying low T3 syndrome was the age irrespective of MG itself.The important factor for moderate general MG are continual glucocortical hormone therapy and hypoalimentation.Conclusion MG involves different muscles.The mechanism underlying MG accompanying low T3 syndrome is also different.