老年PCI患者氯吡格雷药物依从性的影响因素研究

Influencing factors for clopidogrel compliance in old patients after percutaneous coronary implantation

目的研究老年经皮冠状动脉支架置入术(Percutaneous Coronary Implantation,PCI)患者氯吡格雷药物的依从性影响因素。方法对150例老年冠脉支架术后的患者服氯吡格雷12个月遵医行为的影响因素进行调查,并分别于3、6、9、12个月评定患者的遵医行为。结果服药后第9-12个月的依从性最差,影响依从性的因素中健忘占53.13%,知识缺乏占21.87%,经济因素占15.63%,药物不良反应及其他占9.37%。结论老年PCI患者在术后9-12个月期间应该加强健康教育,提高药物依从性。

Objective To study the influencing factors for clopidogrel compliance in old patients after percutaneous coronary implantation（PCI）. Methods Influencing factors for clopidogrel compliance in 150 old patients after PCI were studied 3, 6, 9 and 12 months after administration of clopidogrel. Results The poorest clopidogrel compliance was observed 9-12 months after administration of clopidogrel. Amnesia, lack of knowledge, economic status and adverse drug reaction accounted for 53.13%, 21.87%, 15.63% and 9.37%, respectively, of all the influencing factors. Conclusion Health education should be strengthened in old patients 9-12 months after PCI in order to improve their clopidogrel compliance.