甲状腺功能亢进性心脏病不同的治疗方法效果比较

Comparison of Hyperthyroidism Complicating Hyperthyroid Heart Disease by Different Treatment Methods

目的:探讨甲状腺功能亢进性心脏2种治疗方法的比较。方法:100例甲状腺功能亢进性心脏病病人随机分为两组,对照组50例,常规服丙硫氧嘧啶加倍他乐克;治疗组50例,在常规治疗基础上加用黄芪注射液,连用14d为1个疗程,,观察FT3、FT4、TSH、左室射血分数(LVEF)、左室舒张末内径(LVEDD)、左室收缩末内径(LVESD)、每搏搏出量(SV)、每分输出量(CO)等指标。结果:治疗组总有效率43例(86.0)%明显高于对照组33例(66.0)%;治疗组LVEF、LVEDD、LVESD、SV及CO治疗前后比较均有显著性差异(P均<0.01);治疗组LVEF、SV与对照组比较,差异有显著性(P<0.01);永久性甲减发生率两组间差异无显著意义(P>0.05)。结论:黄芪注射液联合倍他乐克治疗甲状腺功能亢进性心脏病疗效确切。

Objective：To investigate of hyperthyroidism complicating hyperthyroid heart disease by two kinds of treatment methods.Methods：100 cases with hyperthyroidism complicating hyperthyroid heart disease were randomly divided into two groups,The control group（n=50）,conventional propylthiouracil plus metoprolol;Treatment group（n=50） on the basis of conventional therapy was added injection of astragalus,for 14 d as a course of treatment,The index of FT3、 FT4、sTSH、left ventricular ejection fraction （LVEF）、left ventricular end-diastolic diameter （LVEDD）、left ventricular end-systolic diameter（LVESD）、SV stroke volume（SV）、per minute output（CO） were observed.Results：The total effective rate of 43 cases （86.0）% were significantly higher in 33 cases （66.0）%（）;The index of LVEF、 LVEDD、LVESD、SV and CO in treatment group before and after treatment were significantly different （P all 0.01 ）;The index of LVEF、SV compared with the control group,the difference were significant different（P〈0.01）;The rate of hypothyroidism in two groups were no significant difference（P〈0.05）.Conclusions：The curative effect of Astragalus combined metoprolol were precise in patients with hyperthyroidism complicating hyperthyroid heart disease.