燃煤型慢性砷毒接触者发砷含量的比较研究

Comparative Study on the Hair Arsenic Contents from Persons Exposed Arsenic in the Area of Coal Type Endemic Arsenism

对贵州安龙燃煤型砷中毒病区地方性慢性砷毒接触者发砷含量与年龄、性别、病情的关系进行了研究。结果显示，病区砷中毒患者和亚临床患者发砷含量均呈２０倍以上高于正常对照组；患者发砷含量有随病情轻重程度而增高的倾向；正常人群中发砷含量男高于女的现象在燃煤型砷中毒患者和亚临床患者中不再存在，且反有女性高于男性的倾向。另外，本组患者发砷含量有随年龄增加而增高的趋势，这主要是女性患者发砷含量随年龄增加而增高的因素造成的。上述研究结果表明，发砷含量与环境煤砷污染有密切关系，发砷含量显著升高是燃煤型地方性砷中毒病区存在的主要特征之一；定期发砷含量抽查更宜作为病区的直接监测指标；没有临床表现的病区居民，可能已有亚临床砷中毒患者存在，而对此类患者存在的判断。

We studied the correlation of the hair arsenic contents with age,sex.symptomatic degree from persons exposed arsenic in the area of coal type endemic arsenism in Anlong county of Guizhou province.The results showed that the hair arsenic contents of clinical and subclinical endemic arsenism patients are over 20 times higher than that of normal control,and in the clinical patients,their hair arsenic contents have an upward tendency according to the serious degrees of their symptoms;the male hair arsenic contents in normal persons are obviously higher than the female one,but in the persons exposed arsenic there is not this phenomenon and there is trend of the higher value of the female hair arsenic contents;the hair arsenic contents in those female patients of arsenism increase with the age,which results in the trend of increasing hair arsenic contents with the age in all patients.It suggests that the hair arsenic contents have a close relation to the environmental pollution of coal arsenic,and the obvious increasing of hair arsenic contents in the people of endemic area is one of the main characteristics of the existing area of coal type endemic arsenism;the periodic test of hair arsenic contents are suitable to the direct inspect index in the endemic area ;among the residents without clinical symptoms in this area,there are probably some subclinical endemic arsenism patients,and the hair arsenic contents become much more important indicator for the judgment of such kind of subclinical ptients.