纳洛酮治疗急性脑出血临床疗效观察

The efficacy of Naloxone in the treatment of acute cerebral hemorrhage

目的:观察纳洛酮治疗急性脑出血的疗效。方法:收集2006年1月至2009年12月100例急性脑出血患者,随机分为2组,对照组采用脱水等常规对症治疗,治疗组在对照组治疗基础上加用纳洛酮2.4mg静脉滴注,每天2次。观察2组患者治疗后15d、30d神经功能缺损改善情况的差别。结果:治疗组临床疗效及神经功能缺损评分均优于对照组(P<0.05),具有统计学差异。结论:纳洛酮治疗急性期脑出血可明显改善神经功能,提高疗效。

Objective：To observe the efficacy of Naloxone in the treatment of acute cerebral hemorrhage.Methods：100 cases of cerebral hemorrhage patients from Jan 2006 to Dec 2009 were included into ourstudy.They were randomly divided into two groups.The control group used dehydration and conventional symptomatic treatment, Based on the conventional therapy, the therapeutic group was given naloxone 2.4 mg int ravenously ,bid.The differences of the neurologic impairment improvements between the two groups after treated for15, 30 day were observed.Results：The neurologic impairment score and total effective rates in therapeutic group were better than the control group （P0.05）.Conclusion：Naloxone in the treatment of acute cerebral hemorrhage can be significantly improved neu-rological function.